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Anti-CD157 Antibody

     
  • 1 - Anti-CD157 Antibody AP51717
    Western blot analysis of CD157 expression in HEK293T (A), H446 (B), mouse testis (C), rat testis (D), rat spleen (E) whole cell lysates. (Predicted band size: 35 kD; Observed band size: 36 kD)
  • 3 - Anti-CD157 Antibody AP51717
    Immunofluorescent analysis of CD157 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF/IC
Primary Accession Q10588
Reactivity Human, Mouse, Rat, Mk
Host Rabbit
Clonality Polyclonal
Calculated MW 35724 Da
Additional Information
Gene ID 683
Other Names ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; ADP-ribosyl cyclase 2; Bone marrow stromal antigen 1; BST-1; Cyclic ADP-ribose hydrolase 2; cADPr hydrolase 2; CD157
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD157. The exact sequence is proprietary.
Dilution WB~~WB (1/500 - 1/1000)
IF/IC~~N/A
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name BST1
Function Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR) (PubMed:7805847). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable).
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Expressed in various tissues including placenta, lung, liver and kidney.
Research Areas

REFERENCES

Kaisho T.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329(1994).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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