RASSF2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application ![]()
| WB |
---|---|
Primary Accession | P50749 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 37790 Da |
Gene ID | 9770 |
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Other Names | Ras association domain-containing protein 2, RASSF2, KIAA0168 |
Dilution | WB~~1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | RASSF2 |
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Synonyms | CENP-34 {ECO:0000303|PubMed:20813266}, K |
Function | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. |
Cellular Location | Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 and STK4/MST1 |
Tissue Location | Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
REFERENCES
Burbee D.G.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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