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>   首页   >   产品   >   一抗   >   其他   >   Anti-HEXIM2 Antibody   

Anti-HEXIM2 Antibody

     
  • 1 - Anti-HEXIM2 Antibody AP51895
    Western blot analysis of HEXIM2 expression in HEK293T (A), rat kidney (B) whole cell lysates. (Predicted band size: 32 kD; Observed band size: 42 kD)
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q96MH2
Reactivity Human, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 32419 Da
Additional Information
Gene ID 124790
Other Names Protein HEXIM2; Hexamethylene bis-acetamide-inducible protein 2
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HEXIM2. The exact sequence is proprietary.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name HEXIM2
Function Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:15713661, PubMed:15713662). Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:15713661, PubMed:15713662).
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed
Research Areas

REFERENCES

Petroziello J.,et al.Oncogene 23:7734-7745(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Byers S.A.,et al.J. Biol. Chem. 280:16360-16367(2005).
Yik J.H.N.,et al.J. Biol. Chem. 280:16368-16376(2005).

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