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Anti-Thrombopoietin Antibody

     
  • 1 - Anti-Thrombopoietin Antibody AP52026
    Western blot analysis of Thrombopoietin expression in HepG2 (A), mouse liver (B), rat liver (C) whole cell lysates. (Predicted band size: 33; 37 kD; Observed band size: 38 kD)
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P40225
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 37823 Da
Additional Information
Gene ID 7066
Other Names MGDF; Thrombopoietin; C-mpl ligand; ML; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; MGDF; Myeloproliferative leukemia virus oncogene ligand
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Thrombopoietin. The exact sequence is proprietary.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name THPO
Synonyms MGDF
Function Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Cellular Location Secreted
Research Areas

REFERENCES

de Sauvage F.J.,et al.Nature 369:533-538(1994).
Bartley T.D.,et al.Cell 77:1117-1124(1994).
Foster D.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:13023-13027(1994).
Sohma Y.,et al.FEBS Lett. 353:57-61(1994).
Gurney A.L.,et al.Blood 85:981-988(1995).

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