癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
TUSC1 Rabbit pAb
TUSC1 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
| Primary Accession | Q2TAM9 |
|---|---|
| Reactivity | Mouse |
| Predicted | Pig, Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 23105 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human TUSC1 |
| Epitope Specificity | 131-212/212 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis. |
| Gene ID | 286319 |
|---|---|
| Other Names | Tumor suppressor candidate gene 1 protein, TSG-9, TSG9, TUSC1 |
| Dilution | Flow-Cyt=1ug/Test |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | TUSC1 |
|---|---|
| Tissue Location | Widely expressed at low level. Expressed at higher level in testis, weakly expressed in muscle, colon, lung and spleen Not detected in 3 non small cell lung carcinoma (NSCLC) cell lines with homozygous deletion of the 9p region, while it is down-regulated in 3 other tumor cell lines. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
REFERENCES
Shan Z.,et al.Oncogene 23:6612-6620(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Olsen J.V.,et al.Cell 127:635-648(2006).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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¥ 1,250.00
Cat# AP52275
