RELM alpha Rabbit pAb
RELM alpha Rabbit pAb
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Application
| WB |
|---|---|
| Primary Accession | Q9EP95 |
| Reactivity | Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 11936 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from mouse RELM alpha |
| Epitope Specificity | 51-111/111 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Secreted. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | A family of resistin-like molecules (RELMs) has been identified in rodents and humans. RELM alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM alpha and RELM beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain. RELM alpha and Resistin are secreted exclusively by adipocytes while RELM beta is expressed in the epithelium of the colon and small bowel. The RELMs together with resistin comprise a class of tissue-specific signaling molecules. The physiological role and molecular targets of RELM alpha are still unknown. |
| Gene ID | 57262 |
|---|---|
| Other Names | Resistin-like alpha, Cysteine-rich secreted protein A12-gamma, Cysteine-rich secreted protein FIZZ1, Hypoxia-induced mitogenic factor, Parasite-induced macrophage novel gene 1 protein, RELMalpha, Retnla, Fizz1, Himf, Pmng1 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Retnla |
|---|---|
| Synonyms | Fizz1, Himf, Pmng1 |
| Function | Probable hormone. Plays a role in pulmonary vascular remodeling. |
| Cellular Location | Secreted. |
| Tissue Location | Highest levels in adipose tissue. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
REFERENCES
Holcomb I.N.,et al.EMBO J. 19:4046-4055(2000).
Steppan C.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:502-506(2001).
Loke P.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Rajala M.W.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
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