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RELM alpha Rabbit pAb

RELM alpha Rabbit pAb

     
  • 1 - RELM alpha Rabbit pAb AP52317
    Sample:
    Liver (Mouse) Lysate at 40 ug
    Primary: Anti-RELM alpha (AP52317) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 9 kD
    Observed band size: 14 kD
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9EP95
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 11936 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from mouse RELM alpha
Epitope Specificity 51-111/111
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBCELLULAR LOCATION Secreted.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions A family of resistin-like molecules (RELMs) has been identified in rodents and humans. RELM alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM alpha and RELM beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain. RELM alpha and Resistin are secreted exclusively by adipocytes while RELM beta is expressed in the epithelium of the colon and small bowel. The RELMs together with resistin comprise a class of tissue-specific signaling molecules. The physiological role and molecular targets of RELM alpha are still unknown.
Additional Information
Gene ID 57262
Other Names Resistin-like alpha, Cysteine-rich secreted protein A12-gamma, Cysteine-rich secreted protein FIZZ1, Hypoxia-induced mitogenic factor, Parasite-induced macrophage novel gene 1 protein, RELMalpha, Retnla, Fizz1, Himf, Pmng1
Dilution WB=1:500-2000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name Retnla
Synonyms Fizz1, Himf, Pmng1
Function Probable hormone. Plays a role in pulmonary vascular remodeling.
Cellular Location Secreted.
Tissue Location Highest levels in adipose tissue.
Research Areas

BACKGROUND

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

REFERENCES

Holcomb I.N.,et al.EMBO J. 19:4046-4055(2000).
Steppan C.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:502-506(2001).
Loke P.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Rajala M.W.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).

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