Anti-Fatty Acid Synthase Antibody
Mouse Anti Human Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
| Application  
 | WB, IF, IP | 
|---|---|
| Primary Accession | P49327 | 
| Other Accession | NM_004104 | 
| Reactivity | Human, Mouse, Rat, Monkey | 
| Host | Mouse | 
| Clonality | Monoclonal | 
| Isotype | IgG2a | 
| Immunogen | Purified recombinant human Fatty Acid Synthase protein fragments expressed in E.coli. | 
| Purification | Affinity purified | 
| Calculated MW | 273427 Da | 
| Gene ID | 2194 | 
|---|---|
| Other Names | [Acyl-carrier-protein] S acetyltransferase;[Acyl-carrier-protein] S malonyltransferase;3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase;3-oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl-[acyl-carrier-protein] synthase;Enoyl-[acyl-carrier-protein] | 
| Dilution | WB~~1:1000 IF~~1:50~200 IP~~N/A | 
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. | 
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | 
| Name | FASN | 
|---|---|
| Synonyms | FAS | 
| Function | Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. | 
| Cellular Location | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV | 
| Tissue Location | Ubiquitous. Prominent expression in brain, lung, liver and mammary gland. | 
Research Areas
                                
                                                        For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
                                Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.

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