癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-Wnt3 Antibody
Mouse Monoclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | P56703 |
| Other Accession | NM_030753 |
| Reactivity | Transfected |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | lgG1 |
| Immunogen | Purified recombinant human Wnt3 protein fragments expressed in E.coli. |
| Purification | Affinity purified |
| Calculated MW | 39645 Da |
| Gene ID | 7473 |
|---|---|
| Other Names | Int 4;INT4;MGC131950;MGC138321;MGC138323;Proto-oncogene Int-4 homolog;Proto-oncogene Wnt-3;wingless type MMTV integration site family member 3;Wnt 3 proto oncogene protein;WNT 3 proto oncogene protein precursor;wnt3;WNT3_HUMAN. |
| Dilution | WB~~1:1000 |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | WNT3 |
|---|---|
| Synonyms | INT4 |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:26902720). Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge (By similarity). Required for normal embryonic development, and especially for limb development (PubMed:14872406). |
| Cellular Location | Secreted, extracellular space, extracellular matrix. Secreted |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
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