癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-PSA Mouse mAb
Purified Mouse Monoclonal Antibody (Mab)
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC, FC |
|---|---|
| Primary Accession | P07288 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monclonal Antibody |
| Isotype | Mouse IgG1 |
| Immunogen | Purified recombinant fragment of KLK3 (aa26-251) expressed in E. Coli. |
| Purification | Acites |
| Calculated MW | 28741 Da |
| Antigen Region | aa26-251 |
| Gene ID | 354 |
|---|---|
| Other Names | APS; PSA; hK3; KLK2A1; KLK3 |
| Dilution | WB~~1:1000 IHC~~1:1000 FC~~1:10~50 |
| Format | Ascitic fluid containing 0.09% (W/V) sodium azide. |
| Storage | Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | KLK3 |
|---|---|
| Synonyms | APS |
| Function | Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. |
| Cellular Location | Secreted. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Kallikrein-related peptidase 3.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
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