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Histone H2A Rabbit pAb

     
  • 1 - Histone H2A Rabbit pAb AP53575
    Western blot detection of Histone H2A in K562,C6 cell lysates using Histone H2A Rabbit pAb(1:1000 diluted).Predicted band size:14kDa.Observed band size:14kDa.
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Product Information
Primary Accession P04912
Host Rabbit
Clonality Polyclonal Antibody
Calculated MW 13989 Da
Additional Information
Gene ID 852283
Other Names Histone H2A.2, HTA2, H2A2
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name HTA2
Synonyms H2A2
Function Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Research Areas

BACKGROUND

Swiss-Prot Acc.P04912.Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

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