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SEC61A Rabbit pAb

     
  • 1 - SEC61A Rabbit pAb AP53587
    Western blot detection of SEC61A in K562,C6,3T3 cell lysates using SEC61A Rabbit pAb(1:1000 diluted).Predicted band size:52kDa.Observed band size:40kDa.
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Product Information
Primary Accession Q9H9S3
Host Rabbit
Clonality Polyclonal Antibody
Calculated MW 52248 Da
Additional Information
Gene ID 55176
Other Names Protein transport protein Sec61 subunit alpha isoform 2, Sec61 alpha-2, SEC61A2
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name SEC61A2
Function Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.
Cellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P61619}; Multi-pass membrane protein
Research Areas

BACKGROUND

Swiss-Prot Acc.Q9H9S3.Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins .

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