SEC61A Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
| Primary Accession | Q9H9S3 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal Antibody |
| Calculated MW | 52248 Da |
| Gene ID | 55176 |
|---|---|
| Other Names | Protein transport protein Sec61 subunit alpha isoform 2, Sec61 alpha-2, SEC61A2 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SEC61A2 |
|---|---|
| Function | Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P61619}; Multi-pass membrane protein |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Swiss-Prot Acc.Q9H9S3.Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins .
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Discontinued
Cat# AP53587
















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