Anti-Calpain 3 Antibody

Western blot analysis of Calpain 3 expression in mouse muscle (A), rat muscle (B) whole cell lysates.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB
Primary Accession	P20807
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Calculated MW	94254 Da

Additional Information
Gene ID	825
Other Names	CANP3; CANPL3; NCL1; Calpain-3; Calcium-activated neutral proteinase 3; CANP 3; Calpain L3; Calpain p94; Muscle-specific calcium-activated neutral protease 3; New calpain 1; nCL-1
Target/Specificity	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Calpain 3. The exact sequence is proprietary.
Dilution	WB~~1/500 - 1/1000
Format	Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
Storage	Store at -20 °C.Stable for 12 months from date of receipt

Protein Information
Name	CAPN3 (HGNC:1480)
Synonyms	CANP3, CANPL3, NCL1
Function	Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329).
Cellular Location	Cytoplasm. Nucleus, nucleolus
Tissue Location	Isoform I is skeletal muscle specific.