癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-PEX14 Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9FXT6 |
| Reactivity | Arabidopsis thaliana |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 55595 Da |
| Gene ID | 836402 |
|---|---|
| Other Names | PED2; Peroxisomal membrane protein PEX14; Peroxin-14; AtPEX14; Peroxisome biogenesis protein 14; Pex14p; Protein PEROXISOME DEFECTIVE 2 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of arabidopsis thaliana PEX14. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/2000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PEX14 {ECO:0000303|PubMed:11060021} |
|---|---|
| Synonyms | PED2 |
| Function | Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (PubMed:11060021, PubMed:11978862, PubMed:17478547, PubMed:19594707). The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity). Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity). |
| Cellular Location | Peroxisome membrane; Single-pass membrane protein {ECO:0000250|UniProtKB:Q642G4} |
| Tissue Location | Expressed in flowers, siliques, leaves and roots. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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