癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SLCO3A1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q9UIG8 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 76553 Da |
| Gene ID | 28232 |
|---|---|
| Other Names | Solute carrier organic anion transporter family member 3A1, OATP3A1, Organic anion transporter polypeptide-related protein 3, OATP-RP3, OATPRP3, Organic anion-transporting polypeptide D, OATP-D, PGE1 transporter, Sodium-independent organic anion transporter D, Solute carrier family 21 member 11, SLCO3A1, OATP3A1, OATPD, SLC21A11 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLCO3A1 |
|---|---|
| Synonyms | OATP3A1, OATPD, SLC21A11 |
| Function | Putative organic anion antiporter with apparent broad substrate specificity. Recognizes various substrates including thyroid hormone L-thyroxine, prostanoids such as prostaglandin E1 and E2, bile acids such as taurocholate, glycolate and glycochenodeoxycholate and peptide hormones such as L-arginine vasopressin, likely operating in a tissue-specific manner (PubMed:10873595, PubMed:14631946, PubMed:16971491, PubMed:19129463, PubMed:30063921). The transport mechanism, its electrogenicity and potential tissue-specific counterions remain to be elucidated (Probable). Mediates transport of tryptophan, phenyalanine and tyrosine (PubMed:39206635). |
| Cellular Location | [Isoform 1]: Basolateral cell membrane; Multi-pass membrane protein. Note=Localized to the basolateral membrane of choroid plexus epithelium. [Isoform 5]: Apical cell membrane; Multi-pass membrane protein |
| Tissue Location | Generally the expression of isoform 1 is higher than that of isoform 2. [Isoform 2]: Expressed in heart, brain, cerebellum, testis, lung, thyroid, spoleen and liver (PubMed:16971491). In testis, primarily localized to the basal membrane of Sertoli cells and weakly expressed within the tubules (PubMed:16971491, PubMed:35307651). In testis, also present in spermatogonia at different stages. In brain, expressed in the choroid plexus epithelium, at the apical membrane as well as in the subapical intracellular vesicular compartments. In brain, also associated with neuronal bodies and axons in both the gray and the white matters of the frontal cortex (PubMed:16971491) |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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