癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
USP17L24 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P-Leica, IF, WB, FC, E |
|---|---|
| Primary Accession | Q0WX57 |
| Other Accession | C9JPN9, D6RA61, D6R901, D6RJB6, D6RCP7, D6R9N7, D6RBQ6, C9J2P7, C9JLJ4, C9JVI0, A8MUK1, XP_001130410.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 59711 Da |
| Antigen Region | 496-524 aa |
| Gene ID | 728369;728373;728379;728393;728400;728405;728419 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 17-like protein 24, Deubiquitinating enzyme 17, Ubiquitin thioesterase 17, Ubiquitin-specific-processing protease 17, USP17L24 |
| Target/Specificity | This USP17L24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-524 amino acids from the C-terminal region of human USP17L24. |
| Dilution | IHC-P-Leica~~N/A IF~~1:50~200 WB~~1:1000 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | USP17L24 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | USP17L24 |
|---|---|
| Function | Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection. |
| Cellular Location | Nucleus, nucleolus. Endoplasmic reticulum |
| Tissue Location | Expressed in heart, brain, liver and skeletal muscle. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
UBP17 recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins (By similarity).
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