癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
G3PP Rabbit pAb
G3PP Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | P57057 |
| Predicted | Rat, Pig, Human, Mouse, Chicken, Dog, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57648 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human G3PP/SLC37A1 |
| Epitope Specificity | 21-120/533 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Membrane. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | G3PP is a 533 amino acid protein belonging to the major facilitator superfamily. G3PP is a multi-pass membrane protein that acts as a transporter of or glycerol-3-phoshphate between cellular compartments. Glycerol-3-phosphate is produced from glycerol and is an important factor in many biochemical pathways, including glycolysis. G3PP contains 12 putative transmembrane domains and N- and C-terminal Endoplasmic Reticulum (ER) retention signals. G3PP is expressed at highest levels in liver, kidney, small intestine, bone marrow and fetal tissues. |
| Gene ID | 54020 |
|---|---|
| Other Names | Glucose-6-phosphate exchanger SLC37A1, Glycerol-3-phosphate permease, G-3-P permease, Solute carrier family 37 member 1 {ECO:0000312|HGNC:HGNC:11024}, SLC37A1 (HGNC:11024) |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLC37A1 (HGNC:11024) |
|---|---|
| Function | Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in numerous tissues, with highest expression in pancreas, kidney, bone marrow, spleen, liver, small intestine, as well as in fetal brain, liver and spleen |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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