癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
C20orf186 Rabbit pAb
C20orf186 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | P59827 |
| Reactivity | Mouse |
| Predicted | Rat, Dog, Human, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 65055 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human C20orf186 |
| Epitope Specificity | 501-600/614 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Secreted (By similarity). Cytoplasm. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | LPLUNC4 is a 614 amino acid secreted protein that belongs to the BPI/LBP/PLUNC superfamily. Expressed in nasal tissue, LPLUNC4 has the capacity to recognize and bind specific classes of odorants serving as a primary defense mechanism in the mucosa. LPLUNC4 is encoded by a gene which maps to a BPI/LBP/PLUNC gene cluster on human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome |
| Gene ID | 149954 |
|---|---|
| Other Names | BPI fold-containing family B member 4, Ligand-binding protein RY2G5, Long palate, lung and nasal epithelium carcinoma-associated protein 4, BPIFB4, C20orf186, LPLUNC4 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | BPIFB4 |
|---|---|
| Synonyms | C20orf186, LPLUNC4 |
| Function | May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity). |
| Cellular Location | Secreted. Cytoplasm |
| Tissue Location | Expressed in nasal tissue. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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