癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
REG3G Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 文献引用 : 6
- 实验流程
- 背景知识
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q6UW15 |
| Other Accession | NP_001008388.1 |
| Reactivity | Human, Rat, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 19330 Da |
| Antigen Region | 89-116 aa |
| Gene ID | 130120 |
|---|---|
| Other Names | Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 165 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B |
| Target/Specificity | This REG3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids of human REG3G. |
| Dilution | WB~~1:500~1:1000 IHC-P~~1:100~500 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | REG3G Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | REG3G (HGNC:29595) |
|---|---|
| Synonyms | PAP1B |
| Function | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:P42854}. Cytoplasm {ECO:0000250|UniProtKB:P42854} |
| Tissue Location | Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
REG3G might be a stress protein involved in the control of bacterial proliferation (By similarity).
REFERENCES
Taylor-Fishwick, D.A., et al. J. Histochem. Cytochem. 56(2):183-191(2008)
Hamblet, N.S., et al. Pancreas 36(1):1-9(2008)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Laurine, E., et al. Biochim. Biophys. Acta 1727(3):177-187(2005)
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