癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KIAA1109 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q2LD37 |
| Reactivity | Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 555482 Da |
| Gene ID | 84162 |
|---|---|
| Other Names | Transmembrane protein KIAA1109, Fragile site-associated protein, KIAA1109, FSA, KIAA1371 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | BLTP1 (HGNC:26953) |
|---|---|
| Function | Bridge-like lipid transfer protein that functions as molecular bridges between endoplasmic reticulum and the membranes targeted for lipid delivery (PubMed:35491307, PubMed:40269155). Forms a tunnel with multiple beta-grooves that allows the transport of phospholipids (By similarity). Provides phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum (PubMed:35015055). Plays a role in endosomal trafficking and endosome recycling (PubMed:30906834). Also involved in the actin cytoskeleton and cilia structural dynamics (PubMed:30906834). Acts as a regulator of phagocytosis (PubMed:31540829). Required for the formation of endoplasmic reticulum-plasma membrane junctions which are critical for lipid exchange (PubMed:40269155). |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A0A0K3AWP8}; Single-pass membrane protein {ECO:0000250|UniProtKB:A0A0K3AWP8}. Apical cell membrane {ECO:0000250|UniProtKB:A0A0K3AWP8}. Cell membrane {ECO:0000250|UniProtKB:Q12150}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q12150}. Note=Anchors to the endoplasmic reticulum membrane via a single transmembrane helix and bridges the gap to the apical cell membrane. It is unclear if there is a transmembrane region for the cell membrane. {ECO:0000250|UniProtKB:A0A0K3AWP8} |
| Tissue Location | Highly expressed in testis and ovary. Weakly or not expressed in other tissues. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
