癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
KIF19 Rabbit pAb
KIF19 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q2TAC6 |
| Reactivity | Human |
| Predicted | Rat, Pig, Mouse, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 111332 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human KIF19 |
| Epitope Specificity | 701-800/998 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Kinesins also play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Belonging to the Kinesin-like protein family, KIF19 is a 998 amino acid protein that contains one kinesin-motor domain, a domain that creates force in order to bind and move on microtubules. The gene encoding KIF19 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. There are three isoforms of KIF19 that are produced as a result of alternative splicing events. |
| Gene ID | 124602 |
|---|---|
| Other Names | Kinesin-like protein KIF19, KIF19 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KIF19 |
|---|---|
| Function | Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, cilium. Note=Localizes to cilia tips |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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