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SCAND2 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, IHC-F, IF, ICC, E
Primary Accession Q9GZW5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 34217 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human SCAND2
Epitope Specificity 1-100/306
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBCELLULAR LOCATION Nuclear
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions SCAND2 is a 306 amino acid nuclear protein that may play a role in the mechanism of transcriptional regulation. SCAND2 contains one SCAN box domain and, unlike most SCAN box domain-containing proteins, is devoid of a C2H2-type zinc-finger domain. The SCAN box domain is a conserved leucine rich motif, approximately 60 amino acids in length, that participates in protein-protein interactions. The SCAND2 gene is a fusion gene created by the retropositioning of a PHD2 (also known as EGLN1) gene copy from chromosome 1 onto an ancestral SCAN zinc finger gene, followed by exon shuffling. The resulting SCAND2 gene product has an N-terminal SCAN domain and a C-terminus derived from the PHD2 gene. SCAND2 exists as 2 isoforms produced by alternative splicing.
Additional Information
Other Names Putative SCAN domain-containing protein SCAND2P, SCAN domain-containing protein 2 pseudogene, SCAND2P, SCAND2
Dilution IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Format0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Protein Information
Name SCAND2P
Synonyms SCAND2
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187}.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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