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SPOCK3 Rabbit pAb

SPOCK3 Rabbit pAb

     
  • 1 - SPOCK3 Rabbit pAb AP56793
    Sample: 293T Cell (Human) Lysate at 40 ug
    Primary: Anti-SPOCK3 (AP56793) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49 kD
    Observed band size: 48 kD
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9BQ16
Reactivity Human
Predicted Rat, Dog, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 49429 Da
Physical State Liquid
Immunogen KLH conjugated synthetic peptide derived from human SPOCK3
Epitope Specificity 181-280/436
Isotype IgG
Purity affinity purified by Protein A
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBCELLULAR LOCATION Secreted, extracellular space, extracellular matrix.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Additional Information
Gene ID 50859
Other Names Testican-3, SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3, SPOCK3, TICN3
Dilution WB=1:500-2000
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name SPOCK3
Synonyms TICN3
Function May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in brain.
Research Areas

BACKGROUND

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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