癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
HMCN2 Rabbit pAb
HMCN2 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q8NDA2 |
| Predicted | Dog, Human, Mouse, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 544006 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human HMCN2 |
| Epitope Specificity | 101-200/5065 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Secreted |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | First discovered in C. elegans, Hemicentins are extracellular matrix (ECM) proteins that contain a single von Willebrand A domain at the amino terminus, more than 40 tandem immunoglobulin domains, multiple tandem epidermal growth factors, and a single fibulin-like carboxy-terminal module. In mammals, Hemicentins are expressed in the ECM of eye, skin and tongue epithelium and in the ECM of some blood vessels. Due to the expression pattern in areas that are subject to a significant amount of stress, it is thought that Hemicentins likely play a role in the architecture of flexible and adhesive cell junctions. Hemicentin-2 is a 5,065 amino acid secreted protein that is expressed in the extracellular matrix. There are three isoforms of Hemicentin-2 that are produced as a result of alternative splicing events |
| Gene ID | 256158 |
|---|---|
| Other Names | Hemicentin-2, HMCN2 (HGNC:21293) |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | HMCN2 (HGNC:21293) |
|---|---|
| Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:A2AJ76}. Cleavage furrow {ECO:0000250|UniProtKB:A2AJ76}. Note=The antibody used to determine subcellular location does not distinguish between HMCN1 and HMCN2 {ECO:0000250|UniProtKB:A2AJ76} |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
终于等到您。ABCEPTA（百远生物）抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息，您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。
如有疑问，联系：0512-88856768 tech-china@abcepta.com.
