MFSD7 Rabbit pAb

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实验流程
背景知识

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	IHC-P, IHC-F, IF
Primary Accession	Q6UXD7
Predicted	Rat, Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Calculated MW	58427 Da
Physical State	Liquid
Immunogen	KLH conjugated synthetic peptide derived from human MFSD7
Epitope Specificity	251-350/560
Isotype	IgG
Purity	affinity purified by Protein A
Buffer	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBCELLULAR LOCATION	Membrane.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions	MFSD7 is a 560 amino acid multi-pass membrane protein that belongs to the major facilitator superfamily. Existing as three alternatively spliced isoforms, MFSD7 is likely a carrier that transports small solutes by using chemiosmotic ion gradients. Significantly, a related protein, MFSD2, may play a role in placenta morphogenesis and may also be involved in adaptive thermogenesis. The gene encoding MFSD7 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Additional Information
Gene ID	84179
Other Names	Solute carrier family 49 member A3 {ECO:0000312\|HGNC:HGNC:26177}, Major facilitator superfamily domain-containing protein 7, Myosin light polypeptide 5 regulatory protein, MYL5, SLC49A3 (HGNC:26177), MFSD7
Dilution	IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

For Research Use Only. Not For Use In Diagnostic Procedures.