癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Myeloid Marker Rabbit pAb
Myeloid Marker Rabbit pAb
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- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q96S97 |
| Reactivity | Human |
| Predicted | Pig, Horse, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35274 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Myeloid Marker |
| Epitope Specificity | 51-150/322 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Membrane. |
| SIMILARITY | Belongs to the MAL family. Contains 2 MARVEL domains. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Myeloid cells originate in the bone marrow during hematopoiesis and encompass all hemopoietic cells except the lymphoid cells (T cells, B cells, NK cells and dendritic cells). Vascular endothelial cells can differentiate from common myeloid progenitors, and these cells that form the bone marrow-derived myeloid lineage express markers such as CD31, von Willebrand factor and Tie2. Other myeloid markers may be used to track certain diseases, such as Kawasaki disease, a self-limited vasculitis that affects many organs, including the skin and mucous membranes, lymph nodes, blood vessel walls and heart. |
| Gene ID | 91663 |
|---|---|
| Other Names | Myeloid-associated differentiation marker, Protein SB135, MYADM |
| Target/Specificity | Widely expressed. Not detected in thymus. |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | MYADM |
|---|---|
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed. Not detected in thymus. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Myeloid cells originate in the bone marrow during hematopoiesis and encompass all hemopoietic cells except the lymphoid cells (T cells, B cells, NK cells and dendritic cells). Vascular endothelial cells can differentiate from common myeloid progenitors, and these cells that form the bone marrow-derived myeloid lineage express markers such as CD31, von Willebrand factor and Tie2. Other myeloid markers may be used to track certain diseases, such as Kawasaki disease, a self-limited vasculitis that affects many organs, including the skin and mucous membranes, lymph nodes, blood vessel walls and heart.
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