癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
NT5DC2 Rabbit pAb
NT5DC2 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q9H857 |
| Reactivity | Human, Rat |
| Predicted | Mouse, Dog, Pig, Horse, Rabbit, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 60719 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human NT5DC2 |
| Epitope Specificity | 251-350/520 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the 5'(3')-deoxyribonucleotidase family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | NT5DC2 (5'-Nucleotidase Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity and 5-nucleotidase activity. An important paralog of this gene is NT5DC3. |
| Gene ID | 64943 |
|---|---|
| Other Names | 5'-nucleotidase domain-containing protein 2, 3.1.3.-, NT5DC2 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | NT5DC2 |
|---|---|
| Function | Promotes dephosphorylation of tyrosine 3-monooxygenase TH which decreases TH catalytic activity and leads to reduced synthesis of catecholamines including dopamine, noradrenaline and adrenaline. The exact mechanism of activity is unknown but may act as a phosphatase or promote the activity of phosphatases or may inhibit phosphorylation by acting as a barrier to interfere with protein kinase access. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q6Q0N3}. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
NT5DC2 (5'-Nucleotidase Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity and 5-nucleotidase activity. An important paralog of this gene is NT5DC3.
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