癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
ZMIZ2 Rabbit pAb
ZMIZ2 Rabbit pAb
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- 实验流程
- 背景知识
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q8NF64 |
| Reactivity | Mouse |
| Predicted | Rat, Human, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 96537 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ZMIZ2 |
| Epitope Specificity | 1-100/920 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Nucleus. Detected at replication foci throughout S phase. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010] |
| Gene ID | 83637 |
|---|---|
| Other Names | Zinc finger MIZ domain-containing protein 2, PIAS-like protein Zimp7, ZMIZ2, KIAA1886, ZIMP7 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ZMIZ2 |
|---|---|
| Synonyms | KIAA1886, ZIMP7 |
| Function | Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. |
| Cellular Location | Nucleus. Note=Detected at replication foci throughout S phase |
| Tissue Location | Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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