癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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NUFIP2 Rabbit pAb
NUFIP2 Rabbit pAb
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- 实验流程
- 背景知识
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q7Z417 |
| Reactivity | Mouse |
| Predicted | Human, Rat, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 76121 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human NUFIP2 |
| Epitope Specificity | 101-200/695 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Nucleus. Cytoplasm. Distribution is cell cycle-modulated, being cytoplasmic in the G2/M phase and accumulating in nucleus during the G1 phase. |
| Post-translational modifications | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | NUFIP2 (NUFIP2, FMR1 Interacting Protein 2) is a Protein Coding gene. Diseases associated with NUFIP2 include Chromosome 17Q11.2 Deletion Syndrome, 1.4-Mb and Chromosome 17Q11.2 Deletion Syndrome. GO annotations related to this gene include poly(A) RNA binding and RNA binding. |
| Gene ID | 57532 |
|---|---|
| Other Names | FMR1-interacting protein NUFIP2, 82 kDa FMRP-interacting protein, 82-FIP, Cell proliferation-inducing gene 1 protein, FMRP-interacting protein 2, Nuclear FMR1-interacting protein 2 {ECO:0000312|HGNC:HGNC:17634}, NUFIP2 (HGNC:17634), KIAA1321 |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | NUFIP2 (HGNC:17634) |
|---|---|
| Synonyms | KIAA1321 |
| Function | Binds RNA. |
| Cellular Location | Nucleus. Cytoplasm. Cytoplasm, Stress granule. Note=Distribution is cell cycle- modulated, being cytoplasmic in the G2/M phase and accumulating in nucleus during the G1 phase (PubMed:12837692) |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
NUFIP2 (NUFIP2, FMR1 Interacting Protein 2) is a Protein Coding gene. Diseases associated with NUFIP2 include Chromosome 17Q11.2 Deletion Syndrome, 1.4-Mb and Chromosome 17Q11.2 Deletion Syndrome. GO annotations related to this gene include poly(A) RNA binding and RNA binding.
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