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TBC1D10A Rabbit pAb
TBC1D10A Rabbit pAb
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- 实验流程
- 背景知识
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9BXI6 |
| Predicted | Human, Mouse, Rat, Dog, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 57118 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human TBC1D10A |
| Epitope Specificity | 1-100/508 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cell projection > microvillus. Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells. |
| SIMILARITY | Contains 1 Rab-GAP TBC domain. |
| Post-translational modifications | Exists in both phosphorylated and non-phosphorylated state. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | TBC1D10A (TBC1 Domain Family Member 10A) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. GO annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is TBC1D10B. |
| Gene ID | 83874 |
|---|---|
| Other Names | TBC1 domain family member 10A, EBP50-PDX interactor of 64 kDa, EPI64 protein, Rab27A-GAP-alpha, TBC1D10A, EPI64, TBC1D10 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | TBC1D10A |
|---|---|
| Synonyms | EPI64, TBC1D10 |
| Function | GTPase-activating protein (GAP) specific for RAB27A and RAB35 (PubMed:16923811, PubMed:30905672). Does not show GAP activity for RAB2A, RAB3A and RAB4A (PubMed:16923811). |
| Cellular Location | Cell projection, microvillus. Note=Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
TBC1D10A (TBC1 Domain Family Member 10A) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. GO annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is TBC1D10B.
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