CARD17 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
Application ![]()
| WB, IHC-P, IHC-F, IF, E |
---|---|
Primary Accession | Q5XLA6 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 11868 Da |
Other Names | Caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, Inhibitory caspase recruitment domain protein, CARD17, INCA |
---|---|
Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4) with 1% BSA, 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
Name | CARD17P |
---|---|
Synonyms | CARD17, INCA |
Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
Cellular Location | Cytoplasm. |
Tissue Location | Ubiquitous.. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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