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ZNF336/GZF1 Rabbit pAb
ZNF336/GZF1 Rabbit pAb
- 产品详情
- 实验流程
- 背景知识
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9H116 |
| Reactivity | Rat |
| Predicted | Human, Mouse, Chicken, Dog, Horse, Rabbit |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 80492 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF336 |
| Epitope Specificity | 541-640/711 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Nucleus. |
| SIMILARITY | Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 BTB (POZ) domain. Contains 10 C2H2-type zinc fingers. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | GZF1 (GDNF Inducible Zinc Finger Protein 1) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding and transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding. |
| Gene ID | 64412 |
|---|---|
| Other Names | GDNF-inducible zinc finger protein 1, Zinc finger and BTB domain-containing protein 23, Zinc finger protein 336, GZF1 (HGNC:15808), ZBTB23, ZNF336 |
| Target/Specificity | Expressed in adult brain, heart, skeletal muscle, kidney and liver. Also detected in fetal brain and kidney, and at lower levels in fetal lung and liver. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | GZF1 (HGNC:15808) |
|---|---|
| Synonyms | ZBTB23, ZNF336 |
| Function | Transcriptional repressor that binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression. |
| Cellular Location | Cytoplasm. Nucleus, nucleoplasm Nucleus, nucleolus. Note=Nuclear localization depends upon NCL. |
| Tissue Location | Expressed in adult brain, heart, skeletal muscle, kidney and liver. Also detected in fetal brain and kidney, and at lower levels in fetal lung and liver. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
GZF1 (GDNF Inducible Zinc Finger Protein 1) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding and transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding.
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