癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
FMN2 Rabbit pAb
FMN2 Rabbit pAb
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- 背景知识
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Reactivity | Mouse, Chicken, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 189 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human FMN2 |
| Epitope Specificity | 401-500/1722 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Expressed almost exclusively in the developing and mature central nervous system. |
| SIMILARITY | Belongs to the formin homology family. Cappuccino subfamily.Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. |
| Post-translational modifications | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | FMN2 is a member or the formin homology family, Cappuccino subfamily. Formin homology (FH) domain proteins play a role in cytoskeletal organization and/or establishment of cell polarity. In mice, FMN2 has been shown to be a maternal effect gene that is expressed in oocytes and is required for progression through metaphase of meiosis I. FMN2 is expressed in the developing and mature central nervous system. |
| Other Names | Formin-2, FMN2 |
|---|---|
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
FMN2 is a member or the formin homology family, Cappuccino subfamily. Formin homology (FH) domain proteins play a role in cytoskeletal organization and/or establishment of cell polarity. In mice, FMN2 has been shown to be a maternal effect gene that is expressed in oocytes and is required for progression through metaphase of meiosis I. FMN2 is expressed in the developing and mature central nervous system.
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