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>   首页   >   产品   >   一抗   >   其他   >   Anti-Caspase 12 Antibody   

Anti-Caspase 12 Antibody

Rabbit polyclonal antibody to Caspase 12

     
  • 1 - Anti-Caspase 12 Antibody AP59889
    Western blot analysis of Caspase 12 expression in HEK293T (A), A549 (B), U2OS (C), mouse brain (D), mouse spleen (E), rat brain (F) whole cell lysates.
  • 2 - Anti-Caspase 12 Antibody AP59889
    Immunohistochemical analysis of Caspase 12 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC
Primary Accession Q6UXS9
Other Accession O08736
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 38907 Da
Additional Information
Gene ID 100506742
Other Names Inactive caspase-12; CASP-12
Target/Specificity Recognizes endogenous levels of Caspase 12 protein.
Dilution WB~~WB (1/500 - 1/1000), IHC (1/100 - 1/200)
IHC~~WB (1/500 - 1/1000), IHC (1/100 - 1/200)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name CASP12
Function May function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF (PubMed:15129283). May lack protease activity (Probable).
Tissue Location Widely expressed, with highest levels in lung.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Caspase 12. The exact sequence is proprietary.

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