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Anti-ORC2 Antibody

     
  • 1 - Anti-ORC2 Antibody AP59930
    Western blot analysis of ORC2 expression in Hela (A), HGC27 (B), U2OS (C), A549 (D) whole cell lysates. (Predicted band size: 65 kD; Observed band size: 66 kD)
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q13416
Reactivity Human, Mouse, Rat, Mk
Host Rabbit
Clonality Polyclonal
Calculated MW 65972 Da
Additional Information
Gene ID 4999
Other Names ORC2L; Origin recognition complex subunit 2
Target/Specificity KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ORC2. The exact sequence is proprietary.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name ORC2
Synonyms ORC2L
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
Cellular Location Nucleus.
Research Areas
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