癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Anti-FGF13 Antibody
Rabbit polyclonal antibody to FGF13
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- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q92913 |
| Other Accession | P70377 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 27564 Da |
| Gene ID | 2258 |
|---|---|
| Other Names | FHF2; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2 |
| Target/Specificity | Recognizes endogenous levels of FGF13 protein. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | FGF13 (HGNC:3670) |
|---|---|
| Synonyms | FHF2 |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channel transport and function (PubMed:15282281, PubMed:33245860, PubMed:36696443). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity). |
| Cellular Location | [Isoform 1]: Nucleus [Isoform 3]: Cytoplasm. Nucleus [Isoform 5]: Cytoplasm {ECO:0000250|UniProtKB:P61329}. Nucleus {ECO:0000250|UniProtKB:P61329} |
| Tissue Location | Ubiquitously expressed. Predominantly expressed in the nervous system. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FGF13. The exact sequence is proprietary.
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Cat# AP60669
