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>   首页   >   产品   >   一抗   >   其他   >   Anti-DOK7 Antibody   

Anti-DOK7 Antibody

Rabbit polyclonal antibody to DOK7

     
  • 1 - Anti-DOK7 Antibody AP60726
    Western blot analysis of DOK7 expression in HEK293T (A), mouse brian (B), rat brain (C) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q18PE1
Other Accession Q18PE0
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 53097 Da
Additional Information
Gene ID 285489
Other Names C4orf25; Protein Dok-7; Downstream of tyrosine kinase 7
Target/Specificity Recognizes endogenous levels of DOK7 protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name DOK7
Synonyms C4orf25
Function Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Cellular Location Cell membrane; Peripheral membrane protein. Synapse. Note=Accumulates at neuromuscular junctions.
Tissue Location Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human DOK7. The exact sequence is proprietary.

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