VIP Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC-P, FC, E |
---|---|
Primary Accession | P01282 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 19169 Da |
Antigen Region | 139-167 aa |
Gene ID | 7432 |
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Other Names | VIP peptides, Intestinal peptide PHV-42, Peptide histidine valine 42, Intestinal peptide PHM-27, Peptide histidine methioninamide 27, Vasoactive intestinal peptide, VIP, Vasoactive intestinal polypeptide, VIP |
Target/Specificity | This VIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-167 amino acids from the C-terminal region of human VIP. |
Dilution | WB~~1:1000 IHC-P~~1:100~500 FC~~1:10~50 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | VIP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | VIP (HGNC:12693) |
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Function | [Vasoactive intestinal peptide]: VIP is a neuropeptide involved in a diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VPR1) and VIP receptor 2 (VPR2) (PubMed:1318039, PubMed:36385145, PubMed:8933357). Abundantly expressed throughout the CNS and peripheral nervous systems where they primarily exert neuroprotective and immune modulatory roles (PubMed:3456568). Also causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder (PubMed:15013843). |
Cellular Location | Secreted. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
VIP belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder.
REFERENCES
Lu,Y., Neurogastroenterol. Motil. 21 (7), 754-E47 (2009)
Zhu,L., Int J Gynaecol Obstet 105 (3), 223-225 (2009)

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