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PAI2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PAI2 Antibody (Center) AP6562c
    Western blot analysis of PAI2 antibody (Center) (Cat. #AP6562c) in NCI-H460 cell line lysates (35ug/lane). PAI2 (arrow) was detected using the purified Pab.
  • 14 - PAI2 Antibody (Center) AP6562c
    PAI2 Antibody (Center) (Cat. #AP6562c) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P05120
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46596 Da
Antigen Region 116-144 aa
Additional Information
Gene ID 5055
Other Names Plasminogen activator inhibitor 2, PAI-2, Monocyte Arg-serpin, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor, SERPINB2, PAI2, PLANH2
Target/Specificity This PAI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human PAI2.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAI2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINB2
Synonyms PAI2, PLANH2
Function Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Cellular Location Cytoplasm. Secreted, extracellular space.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

PAI2 inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.

REFERENCES

Di Bernardo,M.C., Lung Cancer 65 (2), 237-241 (2009)
Almeida-Vega,S., Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2), G414-G423 (2009)

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