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>   首页   >   产品   >   一抗   >   精选抗体   >   磷酸化抗体   >   IL-4Rα (phospho Tyr497) Polyclonal Antibody   

IL-4Rα (phospho Tyr497) Polyclonal Antibody

     
  • 1 - IL-4Rα (phospho Tyr497) Polyclonal Antibody AP67492
    Western Blot analysis of 293 cells using Phospho-IL-4Rα (Y497) Polyclonal Antibody
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IF
Primary Accession P24394
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 89658 Da
Additional Information
Gene ID 3566
Other Names IL4R; IL4RA; 582J2.1; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD antigen CD124
Dilution WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
IHC-P~~N/A
IF~~1:50~200
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name IL4R
Synonyms IL4RA
Function Receptor for both interleukin 4 and interleukin 13 (PubMed:17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Isoform 1 and isoform 2 are highly expressed in activated T-cells
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

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