GCP3 Polyclonal Antibody

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P
Primary Accession	Q96CW5
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Calculated MW	103571 Da

Additional Information
Gene ID	10426
Other Names	TUBGCP3; GCP3; Gamma-tubulin complex component 3; GCP-3; hGCP3; Gamma-ring complex protein 104 kDa; h104p; hGrip104; Spindle pole body protein Spc98 homolog; hSpc98
Dilution	WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. IHC-P~~N/A
Format	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions	-20℃

Protein Information
Name	TUBGCP3
Synonyms	GCP3
Function	Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed:38305685, PubMed:38609661, PubMed:39321809, PubMed:9566967). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed:38305685, PubMed:38609661, PubMed:39321809).
Cellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Tissue Location	Ubiquitously expressed.