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KV9.2 Polyclonal Antibody

     
  • 1 - KV9.2 Polyclonal Antibody AP70699
    Western Blot analysis of various cells using KV9.2 Polyclonal Antibody
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9ULS6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 54237 Da
Additional Information
Gene ID 3788
Other Names KCNS2; KIAA1144; Potassium voltage-gated channel subfamily S member 2; Delayed-rectifier K(+) channel alpha subunit 2; Voltage-gated potassium channel subunit Kv9.2
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name KCNS2 (HGNC:6301)
Synonyms KIAA1144
Function Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:O35174}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O35174}. Note=May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 or KCNB2 {ECO:0000250|UniProtKB:O35174}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage- gated potassium channel activation and deactivation rates of KCNB1 and KCNB2.

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