mPRα Polyclonal Antibody
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Application
| WB, IHC-P |
|---|---|
| Primary Accession | Q86WK9 |
| Reactivity | Human, Rat, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39719 Da |
| Gene ID | 164091 |
|---|---|
| Other Names | PAQR7; MRPA; Membrane progestin receptor alpha; mPR alpha; Progestin and adipoQ receptor family member 7; Progestin and adipoQ receptor family member VII |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. IHC-P~~1:50~200 |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PAQR7 (HGNC:23146) |
|---|---|
| Synonyms | MRPA |
| Function | Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).
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