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mPRα Polyclonal Antibody

     
  • 1 - mPRα Polyclonal Antibody AP71008
    Western Blot analysis of 293 cells using mPRα Polyclonal Antibody
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession Q86WK9
Reactivity Human, Rat, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 39719 Da
Additional Information
Gene ID 164091
Other Names PAQR7; MRPA; Membrane progestin receptor alpha; mPR alpha; Progestin and adipoQ receptor family member 7; Progestin and adipoQ receptor family member VII
Dilution WB~~Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
IHC-P~~1:50~200
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name PAQR7 (HGNC:23146)
Synonyms MRPA
Function Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder
Research Areas

BACKGROUND

Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).

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