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Olfactory receptor 1A1 Polyclonal Antibody

     
  • 1 - Olfactory receptor 1A1 Polyclonal Antibody AP71463
    Western Blot analysis of various cells using Olfactory receptor 1A1 Polyclonal Antibody
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9P1Q5
Reactivity Human, Rat, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 34565 Da
Additional Information
Gene ID 8383
Other Names OR1A1; Olfactory receptor 1A1; Olfactory receptor 17-7; OR17-7; Olfactory receptor OR17-11
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
E~~N/A
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name OR1A1 {ECO:0000303|PubMed:29632183, ECO:0000312|HGNC:HGNC:8179}
Function Olfactory receptor activated by various compounds, such as 3- methyl-2,4-nonanedione, dihydrojasmone, citronellol and carvone (PubMed:17601748, PubMed:27642093, PubMed:27916747, PubMed:28656349, PubMed:35686936). Ligand-binding causes a conformation change that triggers signaling via G(s)-class of G alpha protein GNAL/G(olf), mediating activation of adenylate cyclase activity and increased production of cAMP, initiating a neuronal response that triggers the perception of a smell (PubMed:27916747). Acts as a selective receptor for 3-methyl-2,4-nonanedione, a key food odorant associated with a prune note in oxidized wine and is an aroma determinant in tea and apricots (PubMed:27916747). Also responds specifically to certain nitromusks, notably musk ambrette, and to a lesser extent, musk tibetene and musk xylene (PubMed:29632183).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in the olfactory epithelium.
Research Areas

BACKGROUND

Odorant receptor.

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