Olfactory receptor 1A1 Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application
| WB, E |
|---|---|
| Primary Accession | Q9P1Q5 |
| Reactivity | Human, Rat, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 34565 Da |
| Gene ID | 8383 |
|---|---|
| Other Names | OR1A1; Olfactory receptor 1A1; Olfactory receptor 17-7; OR17-7; Olfactory receptor OR17-11 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. E~~N/A |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | OR1A1 {ECO:0000303|PubMed:29632183, ECO:0000312|HGNC:HGNC:8179} |
|---|---|
| Function | Olfactory receptor activated by various compounds, such as 3- methyl-2,4-nonanedione, dihydrojasmone, citronellol and carvone (PubMed:17601748, PubMed:27642093, PubMed:27916747, PubMed:28656349, PubMed:35686936). Ligand-binding causes a conformation change that triggers signaling via G(s)-class of G alpha protein GNAL/G(olf), mediating activation of adenylate cyclase activity and increased production of cAMP, initiating a neuronal response that triggers the perception of a smell (PubMed:27916747). Acts as a selective receptor for 3-methyl-2,4-nonanedione, a key food odorant associated with a prune note in oxidized wine and is an aroma determinant in tea and apricots (PubMed:27916747). Also responds specifically to certain nitromusks, notably musk ambrette, and to a lesser extent, musk tibetene and musk xylene (PubMed:29632183). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in the olfactory epithelium. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Odorant receptor.
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