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Reg IV Polyclonal Antibody

     
  • 14 - Reg IV Polyclonal Antibody AP72223
    Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
  • 14 - Reg IV Polyclonal Antibody AP72223
    Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
  • 14 - Reg IV Polyclonal Antibody AP72223
    Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, IF, ICC, E
Primary Accession Q9BYZ8
Reactivity Human, Rat, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 18230 Da
Additional Information
Gene ID 83998
Other Names REG4; GISP; RELP; Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV
Dilution IHC-P~~Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
IF~~1:50~200
ICC~~N/A
E~~N/A
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name REG4
Synonyms GISP, RELP
Function Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
Cellular Location Secreted.
Tissue Location Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
Research Areas

BACKGROUND

Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.

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