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ZnT-9 Polyclonal Antibody

     
  • 1 - ZnT-9 Polyclonal Antibody AP73174
    Western Blot analysis of HepG2 cells using ZnT-9 Polyclonal Antibody. Secondary antibody was diluted at 1:20000
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q6PML9
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 63515 Da
Additional Information
Gene ID 10463
Other Names SLC30A9; C4orf1; HUEL; Zinc transporter 9; ZnT-9; Human embryonic lung protein; HuEL; Solute carrier family 30 member 9
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name SLC30A9 (HGNC:1329)
Synonyms C4orf1, HUEL
Function Mitochondrial proton-coupled zinc ion antiporter mediating the export of zinc from the mitochondria and involved in zinc homeostasis, zinc mobilization as well as mitochondrial morphology and health (PubMed:28334855, PubMed:34397090, PubMed:34433664, PubMed:35614220). In nucleus, functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).
Cellular Location Mitochondrion membrane; Multi-pass membrane protein. Nucleus Endoplasmic reticulum. Note=Partial co- localization with endoplasmic reticulum (PubMed:28334855). Linked to mitochondrial ribosomes (PubMed:35614220)
Tissue Location Ubiquitously expressed in fetal and adult tissues and cancer cell lines.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Acts as a zinc transporter involved in intracellular zinc homeostasis (PubMed:28334855). Functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).

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