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GDF-3 Polyclonal Antibody

     
  • 1 - GDF-3 Polyclonal Antibody AP73829
    Western Blot analysis of L929 cells using GDF-3 Polyclonal Antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000
  • 1 - GDF-3 Polyclonal Antibody AP73829
    Western Blot analysis of L929 cells using GDF-3 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
  • 1 - GDF-3 Polyclonal Antibody AP73829
    Western Blot analysis of K562 KB using GDF-3 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q9NR23
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 41387 Da
Additional Information
Gene ID 9573
Other Names GDF3; Growth/differentiation factor 3; GDF-3
Dilution WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name GDF3
Function Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto (PubMed:21805089).
Cellular Location Secreted. Cytoplasm. Note=Mainly accumulated in the cytoplasm
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto (PubMed:21805089).

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