Calretinin Polyclonal Antibody

Western blot analysis of 293T lysis using CALB2 antibody. Antibody was diluted at 1:500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P
Primary Accession	P22676
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Calculated MW	31540 Da

Additional Information
Gene ID	794
Other Names	Calretinin (CR) (29 kDa calbindin)
Dilution	WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. IHC-P~~N/A
Format	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions	-20℃

Protein Information
Name	CALB2 (HGNC:1435)
Synonyms	CAB29
Function	Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways (PubMed:2001709). Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory (By similarity). During embryonic development, it facilitates neuronal differentiation and maturation (By similarity).
Cellular Location	Synapse {ECO:0000250\|UniProtKB:Q08331}. Cell projection, dendrite {ECO:0000250\|UniProtKB:Q08331}. Note=Located in dendrioles, small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell {ECO:0000250\|UniProtKB:Q08331}
Tissue Location	Brain.