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PENK Polyclonal Antibody

     
  • 1 - PENK Polyclonal Antibody AP74012
    Western Blot analysis of NT28 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000
  • 14 - PENK Polyclonal Antibody AP74012
    Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200
  • 14 - PENK Polyclonal Antibody AP74012
    Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P01210
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 30787 Da
Additional Information
Gene ID 5179
Other Names PENK
Dilution WB~~WB 1:500-2000, ELISA 1:10000-20000
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃
Protein Information
Name PENK (HGNC:8831)
Function [Met-enkephalin]: Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
Cellular Location Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen {ECO:0000250|UniProtKB:P01211}. Secreted {ECO:0000250|UniProtKB:P01211}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.

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