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Gremlin-2 Polyclonal Antibody

     
  • 1 - Gremlin-2 Polyclonal Antibody AP74077
    Western blot analysis of RAT-brain lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000
  • 14 - Gremlin-2 Polyclonal Antibody AP74077
    Immunohistochemical analysis of paraffin-embedded human-small-intestine, antibody was diluted at 1:200
  • 14 - Gremlin-2 Polyclonal Antibody AP74077
    Immunohistochemical analysis of paraffin-embedded human-small-intestine, antibody was diluted at 1:200
  • 14 - Gremlin-2 Polyclonal Antibody AP74077
    Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
  • 14 - Gremlin-2 Polyclonal Antibody AP74077
    Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IF, ICC, E
Primary Accession Q9H772
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 19320 Da
Additional Information
Gene ID 64388
Other Names Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus)
Dilution WB~~WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
IHC-P~~WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
IF~~1:50~200
ICC~~N/A
E~~N/A
Format Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.
Storage Conditions-20℃

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name GREM2
Synonyms CKTSF1B2, DAND3, PRDC
Function Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.
Cellular Location Secreted.
Research Areas

BACKGROUND

Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells.

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