Polyclonal Antibody to Thyroglobulin (TG)
Thyroglobulin
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | O08710 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 304473 Da |
| Gene ID | 21819 |
|---|---|
| Other Names | AITD3; TGN |
| Target/Specificity | Mus musculus (Mouse) |
| Dilution | WB~~Western blotting: 0.5-2 µg/mL; Immunohistochemistry: 5-20 µg/mL; Immunocytochemistry: 5-20 µg/mL; Optimal working dilutions must be determined by end user. |
| Format | 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Tg |
|---|---|
| Synonyms | Tgn |
| Function | Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (By similarity). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling (By similarity). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (Probable). One dimer produces 7 thyroid hormone molecules (By similarity). |
| Cellular Location | Secreted. Note=Secreted into the thyroid follicle lumen (PubMed:12782676). Localizes to colloid globules, a structure formed in the thyroid follicle lumen consisting of cross-linked TG arranged in concentric layers (PubMed:12782676) |
| Tissue Location | Specifically expressed in the thyroid gland. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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